I'm not sure on this, but I'm going to tentatively call Get Fuzzy my favorite comic strip (newspaper comics that is) of all time. There's a lot of strong contenders out there, but I can't think of any that combine the continuity and the funny quite so effectively. That and it's not in any way about children. I wonder how much I would have enjoyed it when I was a kid. Who knows.
Anyhow, quick shout out to hello_world who first recommended it to me a few years before the Post picked it up. Good call there.